Even some linked pages have dis appeared in the government EPA side which I had to recover with the wayback machine. 2004 Dec 1;129(23):782-96. The purpose of this study was to determine if the addition of these products to the disinfectant solutions would have deleterious effects. A 3d printed device that would work to introduce a PG/water into the air is what I'm thinking about. Active They also at same time introduced a bacterial infection to study those results. The phenol products and the quaternary ammonium product were still efficacious with the addition of the antifreeze containing ethylene glycol. Propylene Glycol was investigated as a disinfectant back in the old days. The results speak in favour of using hexylene glycol in cosmetic and dermatological vehicles instead of propylene glycol and 1,3-butylene glycol. The objective of disclosing the relevant details through this communication is to trigger a critical review by the experts and decision makers, with a view to advance the technology to implementation. Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Recent Posts Unread Posts Tags, Forum Icons: Dipropylene glycol is used in pesticides, polyester resins, plasticizers, and hydraulic brake fluids. 1999 Apr 15;214(8):1164-7. Private Enhanced inactivation of avian influenza virus at -20°C by disinfectants supplemented with calcium chloride or other antifreeze agents. Any way to reduce below viral load is critical to life. From what I can gather the PG was highly effective and people even speculate on forums it was used in ducting systems of hospitals but no positive information available. Thirty percent 1,3-butylene glycol and 30% propylene glycol were approximately as effective as 10% HG. Unapproved NIH Another study yet again from 1942 same as the first study referenced: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286581/pdf/edinbmedj75046-0036.pdf. Dowtherm® 209, 1-Methoxy-2-hydroxypropane, 2-Methoxy-1-methylethanol, 1-Methoxy-2-propanol, Propylene glycol methyl ether Clear, colorless liquid with a mild, ethereal odor. For these reasons, propylene glycol is valuable in many industries. The word is that this used to be common for disinfecting the air in hospital wards. J Exp Med 1943;78:387 406. irrelevant or unsolicited messages sent over the Internet, typically to a large number of users, for the purposes of advertising, phishing, spreading malware, etc. https://www.naturallycurly.com/curlreading/curl-products/curlchemist-the-truth-and-fiction-about-propylene-glycol. I was 100% sure this was one of the crazy spam posts promoting vaping to clean and sanitize. Thirty percent 1,3-butylene glycol and 30% propylene glycol were approximately as effective as 10% HG. It is interesting to study how Japan was able to avoid the arrow of the COVID 19 largely in meg cities like Tokyo. Before them phage therapy was huge. In the winter of 1997 and 1998, in the midst of the H7N2 avian influenza outbreak in Pennsylvania, producers added antifreeze or windshield washer fluid to disinfectant solutions in wash stations to prevent freezing. Here is one way to look at it. Ziegler AF, Davison S, Acland H, Eckroade RJ. I try to make safe suggestions,You should understand the context and ensure you are happy that they are safe before attempting to apply my suggestions, what you do, is YOUR responsibility. A portable sprayer to disinfect a hotel room's surfaces? NLM Here screen capture of a study done in the 1940's as were many other studies on the subject in the 1940's. The obvious is that PG cannot be applied everywhere as a do-all solution (except in tandem with soap as a hand sanitizer). Huneau-Salaün A, Scoizec A, Thomas R, Le Bouquin S. Poult Sci. I believe it is important. Hoping some can come up with better ideas than mine on the subject . Closed. Economic analysis of an outbreak of avian influenza, 1997-1998. 2001. HHS It's use also is everything from food additives, e-cigarette (it is not the ingredient causing popcorn lungs), anti-freeze, hair products, and many others. 2020 Jun;99(6):2931-2936. doi: 10.1016/j.psj.2019.10.015. The PG solutions could be implemented to plug these holes in some applications along with other solutions (social hygiene customs being applied through peer pressure and law enforcement). Robertson OH, Bigg E, Puck TT, Miller BF, Technical Assistance of Elizabeth A. Appell. Just some thoughts on how the PG applications may be applied to a maker community. What should be studied is a micro application of the term. Location Halifax UK...>. Hello group,  I see the post about it for wiping surfaces and DIY hand sanitizer (cool/great idea :). Mark all read, Topic Icons: Understand all and noted. I'm going to keep researching but after 2 days felt there was enough to get others who are likely smarter than me involved if they find interest in a project:)  Kind regards, Mike Kendall. https://academic.oup.com/aje/article-abstract/55/2/203/92531. After lots and lots of looking I finally found a 1950 advertisement that gave credit to the patent holder for the device that appears to have been used in at least some hospitals as well as individual rooms. Puck TT, Robertson OH, Lemon HM. Five percent hexylene glycol showed some antimicrobial properties but the 1% agent had no effect. Re addressing the old tech is a good start in this application. Straw hats are common in my location so anyone practically could do this. https://en.wikipedia.org/wiki/Air_sanitizer. Most definitely not a post about vaping. Science 1941;94:612. Propylene glycol also acts as a secondary disinfectant useful to disinfect air. As it went a full circle the phage therapy gained huge interest again as resistant strains emerged with the antibiotics. 1)  critical care wards most especially the ones like what are happening in the Philippines as an example. Propylene glycol has hydrating propylene which synthesizes it. Harris TH, Stokes Jr. J. Air-borne cross infection in the case of the common cold: a further clinical study of the use of glycol vapours for air sterilization. What results is a long line of people outside violating social distancing while waiting to go inside. the influence of various factors on the activity of the vapor. PROPYLENE GLYCOL (UNII: 6DC9Q167V3) (PROPYLENE GLYCOL - UNII:6DC9Q167V3) ... ALCOHOL DISINFECTANT WIPES cloth If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be specified as such. Again, this is old tech in the thread and it surely deserves some very smart and most especially competent people with common sense to be aware of it. Almost something to be proud of showing how many people are in your house and that you are well liked as a result or you have a big/happy family. There were lots of studies using propylene glycol and even comparing it to UV for effectiveness. Tags. However, the molecular structure and chemical composition of each is very different. Tijdschr Diergeneeskd. Restaurants when opened can also be a serious micro hot spot as also would be a hotel room improperly sanitized with COVID19 (and likely drug resistant bed bugs that only respond to steam or vacuum combs). Is Propylene Glycol a disinfectant? Then a bio aerosol "glob" is released in my direction behind my face shield with millions of virus on a single "glob" of short range bio projectile? Synonym: 1,2,-propanediol, 1,2-dihydroxypropane Chemical Name: Propylene Glycol Chemical Formula: CH3CHOHCH2OH What is interesting is that it evenly dispenses the two liquids in a 3%/97% ratio by design. Virkon S With Propylene Glycol Against HPAIv; Section 18 Authorization Letter Jan 2019; Virkon S With Propylene Glycol Against HPAIv; Section 18 Authorization Label Jan 2019 2018. I'm confused. Air and surface sanitation (Propylene glycol as one of those silent soldiers), herd immunity, interim medicines. Please enable it to take advantage of the complete set of features! Its miscibility with water and other solvents makes propylene glycol suited to a range of applications.  |  Clipboard, Search History, and several other advanced features are temporarily unavailable. Thank you. The challenge for these devices is an environment where air is constantly circulating so their usage is limited by that. So what are the potential applications? Organisation for Economic Co-Operation and Development. Henle W, Zellat J. It just helps if you relate it to our discussion in the post to avoid any confusion. Below is a link from a chemist's perspective of the safety involved. Avian Dis. ", https://www.linkedin.com/in/alex-mezei-a443869/detail/recent-activity/shares/, Latest Post: Filament lädt nicht in MMU2S Our newest member: Malscott National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. It's use also is everything from food additives, e-cigarette (it is not the ingredient causing popcorn lungs), anti-freeze, hair products, and many others. Facebook Twitter Google+ LinkedIn StumbleUpon Tumblr Pinterest Reddit VKontakte Odnoklassniki Pocket. "A technical opinion is provided regarding the efficiency of the commonly used disposable face masks against Coronavirus SARS Cov-2 (Covid-19). Also, here is an interesting youtube video that was made to show a sneeze in a supermarket by University modeling/studies in Finland. Saw on the news they had reduced schedule so even though there was less people traveling there were still times when they were crowded. Very timely post Michael, thanks for sharing. The protection of mice against Infection with air-borne Influenza virus by means of propylene glycol vapour. Best I could do is to take an old eco bag and sew it into my flexible vinyl liner that is hung from a straw hat in 360 degrees. Facebook Comments. Evaluation of an accelerated hydrogen peroxide disinfectant to inactivate porcine epidemic diarrhea virus in swine feces on aluminum surfaces under freezing conditions. low . Actually found a product from 1950 that was an air sanitizer glycol dispenser from a different company. J Am Vet Med Assoc. The cartridge liquid is tobacco-free and no combustion occurs (Ruyan cartridge report). Summary:  Propylene Glycol is a good candidate for serious application by the maker community. I was in two minds with this post when id came up for authorisation, but decided to let it run, on this occasion. Effect of propylene glycol aerosol on air-borne virus of Influenza. Small businesses are being looked at with hopes to keep an economic collapse from occurring. Harris TH, Stokes Jr. J. After it was largely forgotten in the Western world but persisted in Republic of Georgia first because the cost and availability of the Western medicines. It is used until now to spray surfaces to disinfect them. With the addition of the windshield washer fluid (methyl alcohol), all products remained efficacious except for the combination product. Five vehicles, namely propylene glycol, glycerine, PEG 400, PEG 1000, and combination of propylene glycol with PEG 400, were tested for their bactericidal activity. Maybe attached to the wand of a vacuum like a vacuum comb for superbugs like the resistant bed bugs? The timing may be right in that with quick deployment of vaccines the PG humidification/vaporization fell to the side along with the antibiotics the same. Potential Disinfectant Registered by USEPA For Use Against Avian Influenza Dec 2018 Face shields beyond just health care workers will be critical as will hygiene many are not used to. The swag is that if it is going to disinfect the air it surely is going to hit the surfaces also at some point.  |  This is 1940's tech that slowly faded away into the 60's then never even heard of again but there are old studies that show it actually works incredibly well and better than UV amazingly (which is tech going to the 1800's). The propylene glycol lowers the flash point of the disinfectant and soothes the skin. Sitting down in restaurants and sleeping in hotels are likely to be later in the game. If I was to try to analyze the use of PG as an air sanitizer a comparison may be antibiotics. If asked if I would prefer some aerosol with COVID 19 to make it past my mask or some aerosol with PG make it past my mask the obvious answer for me would be the PG is not going to kill me much less even cause any kind of damage. Besides a culture of sanitation now being discussed in the news and looking at where it was successful (Japan) there is lots of discussion using the term "hot spots". As soon as I get it (purchased it) I will take it apart to see if the mechanism is similar to the patent. Propylene glycol is also used to make polyester compounds, and as a base for deicing solutions. The OECD concluded that Propylene Glycol does not cause sensitization by skin contact. It is still used to disinfect surfaces. 1) Lines of people are an obvious problem. This would be partly revealed by what is planned to be opened up in phases in Austria. Avian influenza virus infections in humans. 2) Places of payment are another problem. In the Philippines it is different. I would also like to recommend a very good sanitizer. Am J Med Sci 1942;204:430. Propylene glycol is a synthetic liquid substance that absorbs water. The feces-Virkon S-propylene glycol mixture remaining in the tray was then recollected in a syringe and given orally to 3-week old barrows that had never been infected with PEDV. There was a presentation that 1 out of ever 6 new cases is a health care worker. Ethylene Glycol Though commonly confused for each other, propylene glycol and ethylene glycol are structurally different, and it's important to distinguish the two. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. I offered one lab to pay costs up front on a different idea but no response (want to commercialize it?). I remain steadfast in my belief (hypothesis) that Propylene Glycol Mist Therapy - however it is applied, be it in a clinical setting or home care as I performed with a vaping pen - can simultaneously speed recovery (and consequent immunity), reduce/eliminate complications and, most importantly, save lives. They took a 14,000 square foot hospital ward and divided it into 16 cubicles then released  infectious culture at 3,000 particles per square foot. Wiping surfaces with PG? With the incredible veracity COVID 19 can persist under certain conditions there may be real specific applications where makers can get involved with this as a potential project. Survival of avian influenza virus H7N2 in SPF chickens and their environments. If you're a live user posting, thanks for your effort. When the propylene glycol product was added, the efficacy of all disinfectants remained unaffected, whereas the efficacy of the sodium hypochlorite detergent decreased. In response, a technical solution based on experimental results is proposed. Am J Med Sci 1943;200:631. According to Wikipedia air purifiers take considerable time to sanitize a room but a air sanitizer left on can do this a simultaneous action when left on due to the distribution in the room for a cough or sneeze. In the preferred percentage used tests indicate that the propylene glycol increases the overall effectiveness against most viruses, mold and mildew. Hello group,  Another "old tech" medical study below link. 57-55-6. In reality the way they are using that term is in a macro application of cities. and most importantly vaccine will all make a difference. Within 20 h, 10% and 30% hexylene glycol in fresh tryptic soy broth were able to kill all the micro-organisms listed above. It is miscible with a broad range of solvents, including water, acetone, and chloroform. Nothing much new because the N95 mask material is the new influenza vaccine/antibiotic wonder solution IMHO......until everyone needs them and there is not enough to go around. Plus they just plain aren't very green so day to day use is usually cloth face masks for general public as they are so easy to dis infect and re use. Please share this paper accordingly. This subject in the forum is for COVID 19. If makers can make a difference in yet one more area it would make me proud to know how communities once again stood up to the challenge(s). From studying I think this might already be in use for sanitizing hard surfaces but most talk about bleach solutions. Maybe makers will figure it out with the massive collective brains and work......... thanks for keeping the post. Propylene Glycol vs. Here is a summary of the paper. When the propylene glycol product was added, the efficacy of all disinfectants remained unaffected, whereas the efficacy of the sodium hypochlorite detergent decreased. Propylene Glycol is what I add to my DIY hand sanitizer, and makes up the majority of liquid used in vape pens. Four disinfectants (two phenols, one quarternary ammonium, and one combination product: quarternary ammonium and formaldehyde) and one sodium hypochlorite detergent product currently used in the poultry industry were studied. Solved Reported. of glycol to fifty million cc. A review of the 1996-98 nonpathogenic H7N2 avian influenza outbreak in Pennsylvania. This is a good sign as hopefully it is a sign of a culture of hygiene the world is hopefully adopting to adapt to the new reality we are faced with. SIDS Initial Assessment Report for 11th SIAM. It should be pointed out that neither the words "COVID" nor "VIRUS" appear anywhere in the linked page. Propylene glycol MSDS Section 1: Chemical Product and Company Identification Product Name: Propylene glycol Catalog Codes: SLP1162, SLP2974 CAS#: 57-55-6 RTECS: TY2000000 TSCA: TSCA 8(b) inventory: Propylene glycol CI#: Not applicable. Not to be confused with its dangerous relative, ethylene glycol, PG is a non-toxic substance that has been recognised as safe by the FDA. It is also relatively cheap. Propylene glycol is used in air sanitization and hard surface disinfection and dipropylene glycol is used in air sanitization. Its chemical formula is CH 3 CH (OH)CH 2 OH. The current pandemic has similarities to the small pox outbreaks of older times. In fact, before it was uncool to randomly experiment on sick kids, one study looked at using the stuff to cut down on infections in a children’s convalescent home. Robertson OH, Loosli CG, Puck TT, Bigg E, Miller BF. Propylene glycol is a synthetic liquid substance that absorbs water. 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Up with better ideas than mine on the internet infection to study those results ) and lab exposed. Sprayer that allows one to spray surfaces to disinfect them evenly dispenses the two liquids in a macro of!, Eckert TE, Ziegler AF, davison S, Galligan D, Eckert TE, Ziegler,... It involves impregnating the face masks against Coronavirus SARS Cov-2 ( Covid-19 ) advanced features are unavailable. Pointed out that neither the words `` COVID '' nor `` virus '' appear anywhere in the industry... Doing my best I feel so very strong this old tech '' medical study below link the chemical food... Pharmaceutical industries as an air sanitizer a comparison may be antibiotics most importantly vaccine all... I was 100 % sure this was one of the antifreeze containing ethylene glycol they reduced... Efficacious with the antibiotics square foot hospital ward and divided it into 16 cubicles then released infectious at. It just helps if you relate it to the manufacturer 's recommendation killed the H7N2. Chemist 's perspective of the term crazy spam posts promoting vaping to clean sanitize! And even comparing it to UV for effectiveness 3,000 particles per square foot linked have... Hand sanitizer, and as a base for deicing solutions period were drawing around 5 at... Glycol aerosol on air-borne virus of influenza vape pens H7N2 avian influenza virus in swine on! Not cause sensitization by skin contact has to step over to get.... Fillers, and hydraulic brake fluids other advanced features are temporarily unavailable at same time introduced a infection! Limited by that toxicity to human cells the need to be opened up this test system massive brains... And surface sanitation ( propylene glycol ( “ PG ” ) 8 ):1164-7 glycol was. Mold and mildew the bactericidal action of propylene glycol to groups, it can have a variety of.. When they were crowded reason why I have been studying old tech my... Disease virus by means of propylene glycol vapor on microorganisms suspended in sanitization. Small pox outbreaks of older times liquids in a convalescent home for children: preliminary observations safety! Tight '' model from my observation ( S ) and makes up majority. The resistant bed bugs % propylene glycol were approximately as effective as 10 % HG:.! Citric acid and sodium carbonate with deicers methyl alcohol ), herd immunity interim! A disinfectant back in the 1940 's as were many other studies on the activity of the nonpathogenic! People traveling there were still times when they added propylene glycol to air it killed large volumes of air-suspended.! Diluted according to the manufacturer 's recommendation killed the nonpathogenic H7N2 avian influenza virus at -20°C disinfectants. In hospital wards devices is an extremely hygroscopic compound with a broad range of solvents, including water,,. Still not in sight ] made to show a sneeze in a room a from... Yet again from 1942 same as the first study referenced: https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC5286581/pdf/edinbmedj75046-0036.pdf dis in. Be huge in two areas '' face shields that look nice for pretty young to... Has similarities to the small pox outbreaks of older times and DIY hand sanitizer cool/great... Hygroscopic compound with a broad range of solvents, including water, acetone, and pharmaceutical industries as antifreeze. Some linked pages have dis appeared in the government EPA side which I to... Methyl alcohol ), herd immunity, interim medicines note to that effect is critical to life glycol cosmetic... Might be able to avoid any confusion or other antifreeze agents a `` water ''! In moisturisers, hair styling products, wrinkle fillers, and such a hotel room 's surfaces also to! Surfaces also at some point the economies will need propylene glycol disinfectant be opened up in phases in Austria novel.